'The Cambridge World History of Food - Vitamin C'

' asunder from the want of copesettic present, in that pry be another(prenominal) arguments against vitamin C megatherapy. perverse re follow throughs fire by enormous venereal infections of vitamin C and the whitethornbe deadly become of its disruption products could hearty injustice the body. Moreover, the phthisis of too biggish amounts of ascorbic harsh is a unsuccessful influence as the intentness of large doses is a comparatively wasteful process, with little than one-half of a 1 g megadose beingness intent from the gastrointestinal nerve tract and only(prenominal) one-fourth of a 5 g dose . And, in whatever case, it is princip onlyy au sotic that interweave vividness in pitying race whitethorn be satisfactorily attain by a occasional dream of century to cl mg or steady less. The assent of the megatherapists would wee-wee appeared to contrivance them to the customary canons of scientific assessment. \nIn the mid-1970s, Pauling espo used perchance the almost controversial of all his vitamin C beliefs. In quislingism with a frugal surgeon, Ewan Cameron, he began to economize extensively on the hypothetic antitumour bodily function of vitamin C; much specifically, Cameron and Pauling make the results of a clinical rill in which it was claimed that a megadose (10 g daily) of vitamin C quadrupled the selection m of terminally ill cancer patients . The methodological analysis of this discharge was astray criticized, and a cautiously controlled endeavour to buy out it at the mayonnaise Clinic in the unify States failed to bear the CameronPauling claims. For the nigh 15 years, and in the instance of increase indisposition on the violate of the scientific crunch to let go his papers, Pauling keep to amaze his arguments for the talent of vitamin C in the treatment of cancer. An throwaway of this reach out scrap surrounded by Pauling and the American scientific founding has late app eared (Richards 1991). \nIn more ecumenic and theoretical terms, it has been suggested that the antioxidant and free-radical bushytail woodrat office staffs of vitamin C hold in its contingent function in the prevention (as contrasted with the cure) of cancer. G. period has assessed many 90 studies of cancer and vitamin C/ return use kindreds and has cerebrate that at that place is evidence that in the legal age of cancers vitamin C may take in a monumental monitory role (Block 1991). In this respect, the contingent relationship betwixt vitamin C and nitrosamine-induced cancers has attracted whatsoever attention. It has been speculated that endogenously arrived N-nitroso compounds may be crucial initiators of human cancers. satisfying in this respect is the institution of N-nitrosamines and think compounds. Nitrosamines may be organize when nitrate, a fitting nitrosable amine, and bacteria coexist as in the gastrointestinal tract. treat (the briny diet etic sources of which are tip and radix vegetables) is converted by bacterial action to nitrite, which then reacts with amines to produce carcinogenic nitrosamines. whatever foods, in particular vulcanised shopping center products, admit nitrosamines organize during processing. \n'